An Investor's Guide to the Global Longevity Market

1. Where Longevity Is Growing Fastest (Geographical Trends)

   
   

While certain countries consistently rank high for overall life expectancy, a different picture emerges when we look at where the most significant gains in longevity have been made in recent years. This growth is often a reflection of improved healthcare, economic development, and public health initiatives.

Key Insights:

• Top-Ranking Countries: The nations with the highest overall life expectancy are often small, wealthy territories such as Monaco (86.5 years), San Marino (85.8 years), and Hong Kong (85.6 years) [1]. Japan (84.8 years) and South Korea (84.4 years) are also consistently at the top of these lists [1].

• Recent Growth: The United States saw a notable increase in life expectancy of 10.8 months in 2023, following a period of decline related to the COVID-19 pandemic [2].

• Historical Trends: Historically, countries in Asia and Africa have shown the largest percentage increases in life expectancy over the last few decades, particularly as they recovered from conflicts or made significant strides in public health [3]. For example, Bangladesh's life expectancy increased from 26 years in 1971 to 73.7 years by 2022 [4]. This highlights that the "fastest growth" often occurs in nations starting from a lower baseline.

Picture 1: Longevity companies by location in 2024 [5]

2. Where Longevity Companies Are Located and What They Do

   
   

The longevity industry, focused on extending not just lifespan but "healthspan," is a rapidly expanding field. The geographical distribution of these companies shows a clear concentration in specific innovation hubs, distinct from the global life expectancy leaders.

Key Insights:

• United States Dominance: The U.S. is the undisputed global leader in the longevity industry, home to 57% of all longevity companies and accounting for 84% of total investment deal volume in 2024 [5]. California, and specifically the San Francisco Bay Area and San Diego, is a major hub, home to prominent companies like Altos Labs (cellular rejuvenation) [6]. New York City is also a key center for investment and startups [5].

• European Hubs: Europe is a significant player, though it represents a smaller share of the global market. London and Cambridge in the UK, Berlin in Germany, and Paris in France are major centers for longevity research and biotech startups [5]. For example, the UK is home to companies like Altos Labs' Cambridge Institute of Science [6]. Switzerland is also a growing hub for specialized clinics and supplement companies, like AVEA [7, 8].

• Asian Emergence: While Asia has a smaller number of companies overall, investments in countries like China and India have been growing significantly [5]. Hong Kong is home to Insilico Medicine, a major AI-driven drug discovery company [9]. Japan also has significant collaborations with major longevity companies [6].

Picture 2: Is Switzerland becoming the longevity capital of Europe?

2.1 The Longevity Industry by Sector

The longevity industry is a diverse ecosystem that includes several key sectors focused on different approaches to extending healthspan.

• Biotechnology & Pharmaceuticals: This is the core of the longevity industry, with companies focused on developing drugs and therapies that directly target the biological mechanisms of aging. These companies are exploring areas like cellular reprogramming, senolytics (drugs that clear out old cells), and gene therapies. Key players include Altos Labs (cellular rejuvenation) and Unity Biotechnology (senolytics) [6, 10].

• Longevity Supplements: This specialized area focuses on creating science-backed nutritional supplements designed to support healthy aging at a cellular level. Companies like AVEA (Switzerland) develop and provide supplements targeting the hallmarks of aging, such as NAD+ decline [7, 8].

• Wearables & Digital Health: This sector creates consumer-facing technology that allows individuals to track and manage their health data. These devices and apps provide real-time insights into sleep, activity, heart rate, and other biomarkers, empowering people to make healthier choices. The Oura Ring, for example, is a smart ring that provides detailed sleep and readiness scores based on a range of biometric data [11].

• Longevity Clinics & Wellness Centers: These are physical and virtual clinics that offer a comprehensive, personalized approach to healthy aging. They often combine advanced diagnostic testing (like genetic and epigenetic tests), regenerative therapies, and wellness plans to optimize a person's health. Prominent examples include Fountain Life in the U.S. [12] and Ayun in Switzerland [13].

Picture 3: Longevity investment breakdown by sectors [5]

Conclusion

While the nations with the highest life expectancies are often a mix of small, wealthy states and developed countries with long-standing public health systems, the innovation driving the future of longevity is heavily concentrated in a few key global hubs. The U.S. leads the charge, followed by Europe and a growing presence in Asia. This suggests a dichotomy: the places with the longest lives are not necessarily the ones creating the most innovation to extend them further. The fastest-growing longevity is not necessarily where the longevity companies are located.

Sources:

[1] World Population Review. (2025). Life Expectancy by Country 2025. Retrieved from https://worldpopulationreview.com/country-rankings/life-expectancy-by-country

[2] AHA News. (2024). CDC: Life expectancy up, mortality down in 2023. Retrieved from https://www.aha.org/news/headline/2024-12-19-cdc-life-expectancy-mortality-down-2023

[3] WHO. (2021). Data by country, Life expectancy and Healthy life expectancy. Retrieved from https://apps.who.int/gho/data/node.main.688?lang=en

[4] TheGlobalEconomy.com. (2022). Bangladesh Life expectancy - data, chart. Retrieved from https://www.theglobaleconomy.com/Bangladesh/life_expectancy/

[5] Longevity.Technology. (2024). Annual longevity investment report 2024 Archives. Retrieved from https://longevity.technology/investment/report/annual-longevity-investment-report-2024/

[6] Wikipedia. (2024). Altos Labs. Retrieved from https://en.wikipedia.org/wiki/Altos_Labs

[7] Longevity Med Summit. (2023). AVEA Life. Retrieved from https://longevitymedsummit.com/avea-life/

[8] no1-cosmetics.de. (n.d.). Avea - Longevity Bundle (Lemon). Retrieved from https://www.no1-cosmetics.de/en/beauty-food/anti-aging/2510/avea-longevity-bundle-lemon

[9] Insilico Medicine. (2025). Main. Retrieved from https://insilico.com/

[10] Wikipedia. (2024). Unity Biotechnology. Retrieved from https://en.wikipedia.org/wiki/Unity_Biotechnology

[11] droracle.ai. (2025). What are the health tracking data and metrics provided by the Oura (Ouraring) ring?. Retrieved from https://www.droracle.ai/articles/136824/what-is-the-data-on-the-oura-ring-for-health-tracking-

[12] Fountain Life. (2025). Longevity Clinic: Definition, Working, Services, Cost, and Treatment. Retrieved from https://www.fountainlife.com/blog/what-is-a-longevity-clinic

[13] Ayun. (2025). Main. Retrieved from https://www.ayun.ch/